Abstract Presentations: Sarcoma

Moderator(s)

• 

  Ann Lee, MD, FACS (she/her/hers)

  Associate Professor
  NYU Langone Health
  New York City, New York, United States
• 

  Malcolm Squires, MD

  Associate Professor of Surgery
  Levine Cancer Institute, Advocate Health, Wake Forest University School of Medicine - Charlotte
  Charlotte, North Carolina, United States

Presentations:

• 10:32 AM - 10:39 AM MST

  P13. Adjuvant CDK 4/6 inhibitors may be associated with delayed recurrence following complete surgical resection of retroperitoneal liposarcoma
  

  Primary Presenter: Luke V. Selby, MD MS FACS FSSO – University of Kansas Medical Center

  Co-Author: Taylor Williams, MD – The Ohio State University Wexner Medical Center

  Co-Author: Taylor Cusick, BS (she/her/hers) – University of Kansas Medical Center

  Co-Author: Jill Haley, DPT – Department of Surgery, University of Kansas Medical Center

  Co-Author: Marium Husain, MD – The Ohio State University Wexner Medical Center

  Co-Author: David Liebner, MD – The Ohio State University Wexner Medical Center

  Co-Author: Benjamin C. Powers, MD – University of Kansas Cancer Center

  Co-Author: Isuru P. Ratnayake, PhD – University of Kansas Medical Center

  Co-Author: Prabhakar Chalise, PhD – Department of Biostatistics & Data Science, University of Kansas Medical Center

  Co-Author: Joal D. Beane, MD – Department of Surgery, The Ohio State University Wexner Medical Center

  Co-Author: Gabriel Tinoco, MD – The Ohio State University Wexner Medical Center

  Co-Author: Valerie P. Grignol, MD – The Ohio State University Wexner Medical Center

  Co-Author: Aubrey C. Swilling, DO, MS – Department of Surgery, University of Kansas Medical Center
• 10:39 AM - 10:46 AM MST

  P14. Refining Patient Selection for Pembrolizumab in Localized Soft Tissue Sarcoma of the Extremity: A Sarculator-Based Reanalysis of the Randomized SU2C-SARC032 Trial
  

  Primary Presenter: Alessandro Gronchi, MD, FSSO – Fondazione IRCCS Istituto Nazionale dei Tumori - Milan

  Primary Author: Siyer Roohani, MD – Princess Margaret Cancer Centre

  Co-Author: Reinhardt Krcek, MD – Princess Margaret Cancer Centre

  Co-Author: Yvonne M. Mowery, MD – UPMC Hillman Cancer Center-University of Pittsburgh

  Co-Author: Lisa Avery, PhD – Princess Margaret Cancer Centre

  Co-Author: Karla V. Ballman, PhD – Mayo Clinic

  Co-Author: Angela M. Hong, MBBS, MMed, PhD, FRANZCR – The University of Sydney

  Co-Author: Scott M. Schuetze, MD – University of Michigan

  Co-Author: Andrew J. Wagner, MD, PhD – Dana Farber Cancer Institute

  Co-Author: Varun monga, MD – UCSF Helen Diller Comprehensive Cancer Center

  Co-Author: Rachel Heise, PhD – Weill Cornell Medicine

  Co-Author: Everett J. Moding, MD, PhD – Stanford University

  Co-Author: Kent J. Weinhold, PhD – Duke University

  Co-Author: Matt van de Rijn, MD, PhD – Stanford University

  Co-Author: Brian Brigman, MD – Duke University

  Co-Author: Richard F. Riedel, MD – Duke University

  Co-Author: David Kirsch, MD, PhD – Princess Margaret Cancer Centre
• 10:46 AM - 10:53 AM MST

  P15. Potency of the new multikinase inhibitor NB003 for Gastrointestinal stromal tumor
  

  Co-Author: Kevin Do, BS – Hospital of the University of Pennsylvania

  Co-Author: Andrew Tieniber, MD – Memorial Sloan Kettering Cancer Center

  Co-Author: Laura Wang, BS – Hospital of the University of Pennsylvania

  Co-Author: Hyunjee Kwak, MD – University of California San Francisco East Bay

  Co-Author: Taylor E. Hartlein, MD (she/her/hers) – University of Pennsylvania

  Co-Author: Montana T. Morris, MD – University of Pennsylvania

  Co-Author: Juan Esteban Perez, MD – Perelman School of Medicine

  Co-Author: Shan Zeng, MD, PhD – Perelman School of Medicine

  Co-Author: Ferdinando Rossi, PhD – Perelman School of Medicine

  Co-Author: Ronald P. DeMatteo, MD – University of Pennsylvania

  Primary Presenter: Iulia Barbur, MD – Hospital of the University of Pennsylvania
• 10:53 AM - 11:00 AM MST

  P16. Localized Drug Delivery for Retroperitoneal Sarcoma (RPS): An Organotypic Model
  

  Primary Author: Ilaria Caturegli, MD, MS (she/her/hers) – Brigham and Women's Hospital

  Co-Author: Rong Liu, MD, PhD – Massachusetts General Hospital

  Co-Author: Victoria Rivera, BSE – Massachusetts General Hospital

  Co-Author: Olivia Taub, BA – Massachusetts General Hospital

  Co-Author: Chandrajit P. Raut, MD MSc (he/him/his) – Mass General Brigham

  Co-Author: Yolonda Colson, MD, PhD – Massachusetts General Hospital

  Primary Presenter: Ilaria Caturegli, MD, MS (she/her/hers) – Brigham and Women's Hospital
• 11:00 AM - 11:07 AM MST

  P17. Impact of surgery on survival in SDH-deficient GISTs: an update from the NIH Wild-Type GIST Clinic
  

  Primary Presenter: Rachael Lowney, MD (she/her/hers) – Surgical Oncology Program/ National Cancer Institute/ National Institute of Health

  Co-Author: Shadin Gabra, MD – Medstar

  Co-Author: Urania Dagalakis, MD – Pediatric Oncology Branch/ National Cancer Institute/ National Institute of Health

  Co-Author: Erika Kaschak, BA – Pediatric Oncology Branch/ National Cancer Institute/ National Institute of Health

  Co-Author: Barbara Thomas, RN – Pediatric Oncology Branch/ National Cancer Institute/ National Institute of Health

  Co-Author: J. Keith Killian, MD – Foundation Medicine

  Co-Author: Paul Meltzer, MD, PhD – Genetics Branch/ National Cancer Institute/ National Institute of Health

  Co-Author: Brigitte Widemann, MD – Pediatric Oncology Branch/ National Cancer Institute/ National Institute of Health

  Co-Author: Mary Frances Wedekind Malone, DO – Pediatric Oncology Branch/ National Cancer Institute/ National Institute of Health

  Co-Author: John Glod, MD, PhD – Pediatric Oncology Branch/ National Cancer Institute/ National Institute of Health

  Co-Author: Andrew M. Blakely, MD – Surgical Oncology Branch / National Cancer Institute / National Institute of Health
• 11:07 AM - 11:14 AM MST

  P18. ERR-α promotes gastrointestinal stromal tumor proliferation via Wnt/β-catenin
  

  Co-Author: Shan Zeng, MD, PhD – Perelman School of Medicine

  Co-Author: Montana T. Morris, MD – University of Pennsylvania

  Co-Author: Juan Esteban Perez, MD – Perelman School of Medicine

  Co-Author: Iulia Barbur, MD – Hospital of the University of Pennsylvania

  Co-Author: Ferdinando Rossi, PhD – Perelman School of Medicine

  Co-Author: Kevin Do, BS – Hospital of the University of Pennsylvania

  Co-Author: Ronald P. DeMatteo, MD – University of Pennsylvania

  Primary Presenter: Taylor E. Hartlein, MD (she/her/hers) – University of Pennsylvania
• 11:14 AM - 11:21 AM MST

  P19. BayeSarc: Bayesian Update of Sarculator for Primary Retroperitoneal Sarcoma
  

  Primary Author: Dario Callegaro, MD (he/him/his) – Istituto Nazionale dei Tumori, Milan, Italy

  Co-Author: Gabriele Tinè, MSc – Fondazione IRCCS Istituto Nazionale dei Tumori

  Co-Author: Dirk Strauss, MD – Royal Marsden Hospital

  Co-Author: Charles Honorè, MD – Institut Gustave Roussy

  Co-Author: Carol Swallow, MD, PhD, FRCSC, FACS (she/her/hers) – Sinai Health System

  Co-Author: Chandrajit P. Raut, MD MSc (he/him/his) – Mass General Brigham

  Co-Author: Julia H. Song, MD (she/her/hers) – Brigham and Women's Hospital

  Co-Author: Piotr Rutkowski, MD – Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology

  Co-Author: Jacek Skoczylas, MD – Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology

  Co-Author: Sylvie Bonvalot, MD – Institut Curie

  Co-Author: Dimitri Tzanis, MD – Institut Curie

  Co-Author: Winan J. van Houdt, MD – Department of Surgery, Netherland Cancer Institute

  Co-Author: Yvonne Schrage, MD – Netherlands Cancer Institute

  Co-Author: Silvia Stacchiotti, MD – Fondazione IRCCS Istituto Nazionale dei Tumori

  Co-Author: Rosalba Miceli, PhD – Fondazione IRCCS Istituto Nazionale dei Tumori

  Co-Author: Alessandro Gronchi, MD, FSSO – Fondazione IRCCS Istituto Nazionale dei Tumori - Milan

  Primary Presenter: Dario Callegaro, MD (he/him/his) – Istituto Nazionale dei Tumori, Milan, Italy
• 11:21 AM - 11:28 AM MST

  P20. Extracellular vesicle–mediated delivery of miR-210 drives angiogenesis in retroperitoneal sarcomas
  

  Primary Author: Sapir Milshtain, NA – Tel Aviv Sourasky Medical Center

  Co-Author: Shani Goldenberg (she/her/hers) – Tel-Aviv Sourasky Medical Center

  Co-Author: Guy Lahat, MD, Prof. (he/him/his) – Tel Aviv Sourasky Medical Center

  Primary Presenter: Shelly Loewenstein, PhD (she/her/hers) – Tel Aviv Sourasky Medical Center
• 11:28 AM - 11:35 AM MST

  P21. Histology, age and prior radiation are associated with germline predisposition risk in surgical patients with soft tissue sarcoma
  

  Primary Presenter: Carlotta Parati, MD (she/her/hers) – Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Lakshana Senthilkumar, MD (she/her/hers) – Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Yufei Deng, MS (she/her/hers) – Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Meg Sheehan, MS – Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Yelena Kemel, MS, ScM – Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Nicholas Fantanza, MS – Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Bhumika Jadeja, MS – Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Mark DIckson, MD – Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Viswatej Avutu, MD – Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

  Co-Author: Olayode Babatunde, MD – Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

  Co-Author: Evan Rosenbaum, MD – Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

  Co-Author: Sujana Movva, MD – Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

  Co-Author: Diana Mandelker, MD – Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Meera R. Hameed, MD – Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Li-Xuan Qin, PhD – Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Samuel Singer, MD, FACS – Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Narasimhan Agaram, MD – Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Zsofia Stadler, MD – Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

  Co-Author: Aimee M. Crago, MD, PhD (she/her/hers) – Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY
• 11:35 AM - 11:42 AM MST

  P22. Myeloid derived suppressor cells drive resistance to IL-15-based immunotherapy in mouse and human sarcoma
  

  Co-Author: Makan Karimzadeh, MD – University of California Davis

  Co-Author: Aryana Razmara, PhD – University of California Davis

  Co-Author: Yeji Cho, BS – University of California Davis

  Co-Author: Sylvia Cruz, MD – University of California Davis

  Co-Author: Marshall Lammers, PhD – University of California Davis

  Co-Author: Natalie Liu, MD – University of California Davis

  Co-Author: Megan Purl, BS – University of California Davis

  Co-Author: Sean Judge, MD – University of California Davis

  Co-Author: William Murphy, PhD – University of California Davis

  Primary Presenter: Robert Canter, MD (he/him/his) – University of California Davis

  Co-Author: Cyrus Sholevar, MD – University of California Davis

  Co-Author: Robert Canter, MD (he/him/his) – University of California Davis
• 11:42 AM - 11:49 AM MST

  P23. Transcriptional heterogeneity in dedifferentiated liposarcoma reveals distinct cell-cycle subtypes
  

  Co-Author: Philip M. Spanheimer, MD (he/him/his) – University of North Carolina, Department of Surgery

  Co-Author: Tarek M. Zikry, PhD – UNC Chapel Hill School of Data Science and Society

  Primary Presenter: Kelly M. Herremans, MD, MS – University of North Carolina
• 11:49 AM - 11:56 AM MST

  P24. Cancer-associated Fibroblast Expression in Sarcomas Varies by Histology and Tumor Grade
  

  Co-Author: Mohamed Sharif, PhD – Roswell Park Comprehensive Cancer Center

  Co-Author: Ankit Patel, MD – Roswell Park Comprehensive Cancer Center

  Co-Author: Gary Mann, MD (he/him/his) – Roswell Park Comprehensive Cancer Center, Department of Surgical Oncology

  Co-Author: Joyce Ohm, PhD – Roswell Park Comprehensive Cancer Center

  Co-Author: Kazuaki Takabe, MD, PhD – Roswell Park Comprehensive Cancer Center

  Primary Presenter: Olivia A. Martin, MD, MS (she/her/hers) – Roswell Park Comprehensive Cancer Center